1/6/2009
Tuesday morning

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I did a weight-loss trial with 51 people comparing 3 diets (alternate use). Panelists weighed themselves 6 times a day for a week (42 readings to get an accurate value of weight before new Diet). 17 people had Diet A 1st for 10 weeks. Similarly, 17 people each were started on Diets B or C.
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Randomised comparison of diets for maintaining obese subjects weight after major weight loss: ad lib, low fat, high carbohydrate diet v fixed energy intake.
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The Group main effect represents any systematic differences due to whether the sequence of diets was (A,B,C) or (B,C,A) or (C,A,B). The Diet main effect represents the effects presumably of interest, that is, whether the three diets differed in amount of weight loss observed. The Sequence effect shows whether being the 1st, 2nd, or 3rd diet in the temporal sequence makes any difference. The remaining 2 d.f. for assorted interactions is unlikely to be interesting, but if significant might indicate something that might be worth pursuing. (The problem with interactions in a Latin square is that GD interactions are confounded with the S main effect, GS with D, and DS with G.) (The mean square for Respondents within Group is the error term, or denominator mean square, against which the mean square for Group is tested; the mean square for Diet X Respondents within Group is the error mean square for Diet, Sequence, and the remaining interaction mean square.)
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