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1/5/2009
Monday morning
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| OBJECTIVES: To compare importance of rate of initial weight loss for long
term outcome in obese patients and to compare efficacy of two different
weight maintenance programmes. DESIGN: Subjects were randomised to either
rapid or slow initial weight loss. Completing patients were re-randomised to
one year weight maintenance programme of ad lib diet or fixed energy intake
diet. Patients were followed up one year later. SETTING: University research
department in Copenhagen, Denmark. SUBJECTS: 43 (41 women) obese s
(body mass index 27-40) who were otherwise healthy living in or around
Copenhagen. INTERVENTIONS: 8 weeks of low energy diet (2 MJ/day) or 17 weeks
of conventional diet (5 MJ/day), both supported by an anorectic compound
(ephedrine 20 mg and caffeine 200 mg thrice daily); one year weight
maintenance programme of ad lib, low fat, high carbohydrate diet or fixed
energy intake diet ( 5 kg at follow up.
RESULTS: Mean initial weight loss was 12.6 kg (95% confidence inte. |
| Reality: If you want to lose weight, the truth is that you really cannot
eat as much as you want of all your favorite foods, but you can still enjoy
your favorite foods in moderation. |
| 1. Pretest weight (42 readings, averaged)
2. 10 weeks of Diet A (or Diet B, or Diet C, in the other two groups)_
3. Post-diet weight #1 (42 readings, averaged)
4. 10 weeks of uncontrolled non-diet
5. New non-diet baseline weight #2 (42 readings, averaged)
6. 10 weeks of Diet B (or Diet C, or Diet A, respectively)
7. Post-diet weight #2 (42 readings, averaged)
8. 10 weeks of uncontrolled non-diet
9. New non-diet baseline weight #3 (42 readings, averaged)
10. 10 weeks of Diet C (or Diet A, or Diet B, respectively)
11. Post-diet weight #3 (42 readings, averaged) |
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| As above, weights were taken in the 10th week. All of the panelists
were then given 10 weeks off to go back to their original (non-trial) diet
and weighed themselves as above before starting a new diet. In the final
10-week period, the panelists went on the Diet they had not tried before. |
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