| OBJECTIVES: To compare importance of rate of initial weight loss for long
term outcome in obese patients and to compare efficacy of two different
weight maintenance programmes. DESIGN: Subjects were randomised to either
rapid or slow initial weight loss. Completing patients were re-randomised to
one year weight maintenance programme of ad lib diet or fixed energy intake
diet. Patients were followed up one year later. SETTING: University research
department in Copenhagen, Denmark. SUBJECTS: 43 (41 women) obese s
(body mass index 27-40) who were otherwise healthy living in or around
Copenhagen. INTERVENTIONS: 8 weeks of low energy diet (2 MJ/day) or 17 weeks
of conventional diet (5 MJ/day), both supported by an anorectic compound
(ephedrine 20 mg and caffeine 200 mg thrice daily); one year weight
maintenance programme of ad lib, low fat, high carbohydrate diet or fixed
energy intake diet ( 5 kg at follow up.
RESULTS: Mean initial weight loss was 12.6 kg (95% confidence inte. |
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| As above, weights were taken in the 10th week. All of the panelists
were then given 10 weeks off to go back to their original (non-trial) diet
and weighed themselves as above before starting a new diet. In the final
10-week period, the panelists went on the Diet they had not tried before. |
